Kembi has been built by scientists, clinicians, investors and operators with proven track records.
>10
FDA-approved therapies
>650
Peer-reviewed publications
A team with the scientific depth, clinical experience, and commercial expertise to take Kembi from discovery to patients.
B.Sc. (Hons) (Pharmacology), PhD
A/Prof Christine Chaffer is head of the Cancer Cell Plasticity Lab at the Garvan Institute of Medical Research and Director of the Cancer Plasticity and Dormancy Program, where her research established plasticity as a validated, druggable target in therapy-resistant cancers. A/Prof Chaffer's high-impact publications in Cell, Science, Cancer Discovery and Nature Cell Biology have fundamentally reshaped understanding of how cancer cells acquire resistance, forming the scientific foundation of Kembi Therapeutics. A/Prof Chaffer is also the leader of the international AllClear research program, which was awarded the first and landmark $25 million collaborative research accelerator grant by the National Breast Cancer Foundation in August 2025.
B.Sc. (Hons) (Pharmacology), L.L.B. (Hons)
Paul Bernath is Managing Director and Australia Office Head at CPP Investments, one of the world's largest institutional investors with C$780.7 billion assets under management as at 31 December 2025, projected to exceed C$1 trillion by 2028. Mr. Bernath leads the Fund's presence in Australia as well as its infrastructure activities across the broader Asia Pacific region (ex. India), and is a member of the Fund's Global Infrastructure Investment Committee. He is also an experienced board member of several large-scale businesses including AirTrunk, Pacific National and WestConnex. Mr. Bernath brings deep expertise in commercial and investment strategy, capital allocation, financing, M&A and governance to Kembi, supporting the company's growth from clinical stage to global biotech.
A.B., M.S.
David Scheer is founder and President of Scheer & Company, a life sciences advisory firm he has led since 1981, with a track record of founding and serving on the board or as chair of companies including Achillion Pharmaceuticals (acquired by Alexion), Viropharma (acquired by Shire/Takeda), OraPharma (acquired by JNJ, now a unit of Valeant) and Esperion Therapeutics (acquired by Pfizer), with collective acquisitions representing over US$7 billion. He is currently a member and chair of the boards of multiple biotechnology companies, including Adela, Ladder Bio and Apriligen, and also serves as a member of the board of directors of BioCT, and on the executive board of the Center for Biomedical Innovation and Technologies at Yale University. Mr. Scheer brings decades of expertise in corporate and pharmaceutical strategy, as well as company development, growth, M&A and governance to Kembi.
B.S., M.D.
Dr. Tony Ho is a seasoned pharmacology R&D leader who serves as Chief Scientific Officer & Senior Science Partner at Pivotal Life Sciences. Dr. Ho was formerly EVP and Head of R&D at CRISPR Therapeutics (where he brought the first CRISPR-based therapy, Casgevy, to the clinic) and SVP and Head of Oncology Integration at AstraZeneca, where he oversaw the development and commercialisation of Lynparza and Imfinzi, with 10 Phase 3 trials designed under his leadership now having obtained positive results. He also led the development and launch of Zioptan and several Phase 3 programs as Head of Neurology and Ophthalmology at Merck. Dr. Ho's expertise encompasses drug discovery and development through successful regulatory approval and commercialisation across oncology, gene editing, and cell therapy.
B.S., M.D., L.Ac
Dr. Mary Tagliaferri is a visionary physician-scientist and biotechnology executive with over 25 years of drug development experience across oncology, immunology and women's health. Currently serving as the Chief Medical Officer of Nektar Therapeutics, she has a proven track record of guiding transformative therapies from early discovery through late-stage global clinical trials and regulatory approval. Dr. Tagliaferri has also held roles as a clinical and regulatory consultant to InterMune, Chief Medical Officer at KangLaiTe USA, as well as Co-Founder, President, and Chief Medical Officer of Bionovo, Inc. Dr. Tagliaferri currently serves on the Board of Directors of Iambic Therapeutics and ADARx Pharmaceuticals and has previously held independent board roles with RayzeBio (Nasdaq: RYZB), Y-mAbs Therapeutics (Nasdaq: YMAB), and Enzo Biochem (NYSE: ENZ).
PhD
Dr. Milind Deshpande is a Venture Partner at RA Capital Management with over 25 years of drug discovery and operational leadership, including roles as President and CEO of Achillion Pharmaceuticals and co-inventor of the first-in-class HCV NS5A inhibitors that led to the approval of Daklinza. Dr. Deshpande is co-founder and board member of Spero Therapeutics, co-founder and chairman of Avilar Therapeutics, was co-founder and CEO of Hyku Biosciences and was CEO of Nayan Therapeutics. He was also Group Leader at Bristol-Myers Squibb for all early stage discovery programs in infectious diseases and neuroscience and has co-authored more than 80 scientific articles. Dr. Deshpande brings deep expertise in small molecule discovery and clinical-stage development to Kembi's drug discovery program.
B.S., M.S.
Elizabeth Woodson is an oncology program leader with a 20-year track record in program management across clinical development. Her experience spans complex multi-indication oncology programs of biologics and small molecules in academic, CRO, and biotech settings, partnering with executive leadership to drive R&D strategy. Most recently, at Istari Oncology, she served as Executive Director of Program Management, leading program management for the LUMINOS trials evaluating lerapolturev across glioblastoma, melanoma, and a multi-indication basket study in solid tumors. Prior to Istari, she supported Phase 2 programs of seviteronel in triple-negative breast cancer and castration-resistant prostate cancer at Innocrin Pharmaceuticals. Ms. Woodson has proven expertise in cross-functional program leadership and the operational demands of first-in-class oncology therapeutics, directly applied to driving KMB-464 through clinical development at Kembi.
B.S.F.S., M.S., J.D.
George Rehm was a founding partner of aeris CAPITAL AG, financial advisor to the foundation of SAP founder Klaus Tschira, where he built its healthcare investing strategy across venture, private equity, and hedge funds. His board and observer positions have spanned Butterfly Networks (IPO), QuantumSi (IPO via SPAC), Adamas Pharmaceuticals (acquired by Supernus Pharma), Genome Dx/Decipher (acquired by Veracyte), and Ion Torrent (acquired by Thermo Fisher). He currently serves on the boards of Artera AI, Inkspace Imaging, and Respond Health, and on the Strategic Advisory Councils of Revalisio Health, iSono Health, and Vizma, and as Senior Mentor at Bakar Labs, UC Berkeley. Prior to aeris, Mr. Rehm spent over 20 years as a lawyer and executive in international licensing, technology transfer, and investment across the US, Europe, and Asia.
Kembi's Scientific Advisory Board brings together leading oncologists and cancer biologists from the world's foremost research institutions.
M.D., FASCO
Memorial Sloan Kettering Cancer Center
Dr. Tiffany A. Traina is an Associate Member at Memorial Sloan Kettering Cancer Centre and Associate Professor of Medicine at Weill Cornell Medicine, and a Fellow of the American Society of Clinical Oncology. She serves as Section Head of the Triple-Negative Breast Cancer Research Program and Vice Chair of the Department of Medicine at MSK, and has held leadership roles including Clinical Director of the Breast Medicine Service and Co-Chair of the Outpatient Operations Committee. Within ASCO, she has served as Chair of the Membership Committee and Co-Chair of the Breast Cancer Guidelines Advisory Group. Dr. Traina has been recognized with the MSK Hirsch Family Clinical Excellence Honor, the Hally Yaccino Steiner Award from Susan G. Komen, the Hero Award from the TNBC Foundation, as well as Castle Connolly Top Doctor and Forbes' Top Breast Cancer Oncologist designations.
Triple Negative Breast Cancer Profile
B.S., PhD
MIT & Whitehead Institute for Biomedical Research
Professor Robert A. Weinberg is a pioneering cancer biologist and co-discoverer of the first human oncogene, whose foundational work on the epithelial-to-mesenchymal transition (EMT) and cancer cell plasticity underpins Kembi's scientific platform. Prof. Weinberg is the Daniel K. Ludwig Professor for Cancer Research at MIT and Core Member, Whitehead Institute for Biomedical Research. He has also received numerous awards over his career, including the Japan Prize, the Salk Institute Medal for Research Excellence, the Breakthrough Prize in Life Sciences, the Wolf Foundation Prize, the Keio Medical Science Foundation Prize, the Harvey Prize, the Sloan Prize as well as the National Medal of Science, and his work has been cited over 400,000 times.
Cancer Biology & EMT Profile
M.D.
Baylor University Medical Center & Texas Oncology
Dr. Joyce O'Shaughnessy is one of the world's foremost breast cancer clinician-scientists, renowned for landmark Phase 3 trials that have defined standard-of-care. Diplomate of the American Board of Internal Medicine and medical oncologist, she holds the Celebrating Women Endowed Chair in Breast Cancer Research at Baylor University Medical Center and serves as Director of Breast Cancer Research at Baylor Charles A. Sammons Cancer Center and Chair of the Breast Disease Committee for Sarah Cannon Research Institute in Dallas, TX. Her research focuses on genotype-phenotype correlations in high-risk breast cancers and immunotherapy for TNBC. Dr. O'Shaughnessy earned her M.D. from Yale University School of Medicine and completed residency at Massachusetts General Hospital and a Fellowship in Medical Oncology at the National Cancer Institute. She is a member of ASCO and AACR, and founder of The School of Breast Oncology.
Breast Cancer Clinical Trials Profile
M.D.
Memorial Sloan Kettering Cancer Center
Dr. Ayca Gucalp is a board-certified medical oncologist whose practice is dedicated exclusively to breast cancer, with a particular focus on triple negative breast cancer (TNBC) and male breast cancer. She has extensive expertise in clinical trial development across early-stage and metastatic settings, evaluating the underlying biology of TNBC to advance more effective and less toxic treatment strategies. Dr. Gucalp earned her medical degree from Albert Einstein College of Medicine and completed residency training in Internal Medicine at New York University Medical Center. She served as Chief Resident at Memorial Sloan Kettering Cancer Center, where she is now Assistant Attending Physician. She holds an appointment as Assistant Professor of Medicine at Weill Cornell Medical College. Dr. Gucalp has received Young Investigator Awards from the Conquer Cancer Foundation of ASCO, the Terri Brodeur Breast Cancer Foundation, the Breast Cancer Alliance, as well as a Career Development Award from the Conquer Cancer Foundation of ASCO.
Breast Cancer & Prevention Profile
MBBS, FRACP, PhD
The Kinghorn Cancer Centre, St. Vincent's Hospital
A/Prof Rachel Dear is a clinical oncologist and translational researcher whose work bridges laboratory discovery and patient care, with a particular focus on personalized cancer medicine and resistance mechanisms in solid tumors. A/Prof Dear is Senior Staff Specialist and Medical Oncologist at The Kinghorn Cancer Centre, St Vincent's Hospital Sydney, and Associate Professor at UNSW Sydney, where her research focuses include breast cancer dormancy and plasticity. In partnership with the Garvan Institute of Medical Research, she leads investigator-initiated clinical trials and brings significant expertise as a principal investigator. A/Prof Dear received her Bachelor of Medicine and Bachelor of Surgery from the University of New South Wales and her PhD in Medicine from the University of Sydney.
Translational Oncology ProfileUnderstand the biology behind our programs.